It's fairly tricky in SR2. I managed to buy all the player housing by getting my character addicted to blackjack and save scumming. It kinda sucks because SR2 saves load you back to the safe house, but I keep a helicopter ready near the casino.
I've managed the intro storyline and also managed the first two stronghold missions, where you must evict homeless people from shanty towns. The first instance is fairly easy, as psychopath Johnny Gat mows down hostiles. I had trouble with the second stronghold as I had to knock over shanty towns, and the nightstick wasn't cutting it. I managed to knock them over with a bag of garbage, plus the homeless hostiles shot their own hideouts up while trying to kill me. I've accidentally picked up a Vice 9 pistol, T3k urban smg, a tombstone shotgun, and a variety of melee weapons. I have not found a way to remove the weapons.
My secret is helicopters. I fly a thompson helicopter everywhere, to avoid running anyone over, and also avoid enemies.