I've not encountered that error, but my computer was originally built in 2011.
I'd suggest the EA answers HQ, but honestly, it's mostly poo.
Did you buy the Trilogy pack? Or did you do the whole shebang with three purchases nonsense I did?
I just checked on steam, if you have Nvidia graphics you can use something called Rivatuner to fix it, but I have ATI.
I originally played Mass Effect on a 2006 MBP, and had no performance issues. I was kind of surprised how smooth it ran back then.